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Publications

Lung Cancer

Gefitinib and chemotherapy combination studies in five novel human non small cell lung cancer xenografts. Evidence linking EGFR signaling to gefitinib antitumor response

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Publications

Breast Cancer

Molecular profiling of patient-derived breast cancer xenografts

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Publications

Breast Cancer

A platform of metastatic bioluminescent PDX: Focus on HBCx14-Luc1 metastatic bioluminescent breast tumorgraft model for preclinical studies

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Publications

Breast Cancer

Bioluminescent orthotopic PDX models of primary pancreatic cancer and residual/metastatic breast cancer to predict efficacy of standard of care and experimental treatments

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Publications

Breast Cancer

XenTech patient-derived xenograft (PDX) panels: a clinically relevant platform for drug efficacy, target validation and predictive biomarker discovery studies

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Publications

Breast Cancer

The sialyl-glycolipid SSEA4 marks a subpopulation of chemotherapy resistant breast cancer cells with mesenchymal features

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Publications

Breast Cancer

Understanding breast cancer resistance to chemotherapy: Characterization of cancer cell sub-populations in residual and relapsed tumors

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Publications

Breast Cancer

The sialyl-glycolipid stage-specific embryonic antigen 4 marks a subpopulation of chemotherapy-resistant breast cancer cells with mesenchymal features

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Publications

Breast Cancer

Cell-autonomous activation of the Interferon/STAT1 pathway in response to genotoxic treatment

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Publications

Breast Cancer

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

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